| Cal Poly (3-6) | L 40-67 | SBC | UA Little Rock | 8-4 | 11/14/2008 | ||
| L 76-81 | vs | CUSA | Rice | 4-8 | 11/20/2008 | Basketball Travelers Tournament | |
| W 76-42 | vs | ASUN | North Florida | 1-9 | 11/21/2008 | Basketball Travelers Tournament | |
| L 64-76 | @ | MW | BYU | 10-1 | 11/22/2008 | Basketball Travelers Tournament | |
| L 57-97 | @ | WAC | Utah St | 10-1 | 11/29/2008 | ||
| W 61-40 | WCC | San Francisco | 6-6 | 12/3/2008 | |||
| W 65-62 | Bsky | Portland St | 7-3 | 12/17/2008 | |||
| L 64-66 | @ | Ind | CS Bakersfield | 3-10 | 12/23/2008 | ||
| L 87-90 OT | WAC | Fresno St | 5-7 | 12/29/2008 | |||
| CS Fullerton (5-7) | L 66-76 | vs | SLC | Texas St | 1-6 | 11/14/2008 | UH-Invitational |
| W 90-76 | @ | WAC | Hawai'i | 8-3 | 11/16/2008 | UH-Invitational | |
| L 75-76 | @ | Bsky | Portland St | 6-4 | 11/23/2008 | ||
| L 69-75 | vs | ACC | Wake Forest | 11-0 | 11/27/2008 | Anaheim Tournament | |
| L 54-79 | vs | WCC | St. Mary's | 9-1 | 11/28/2008 | Anaheim Tournament | |
| W 92-84 OT | vs | A10 | Charlotte | 5-5 | 11/30/2008 | Anaheim Tournament | |
| L 63-84 | @ | SEC | LSU | 10-1 | 12/2/2008 | ||
| W 79-65 | MAC | Central Michigan | 3-8 | 12/6/2008 | |||
| L 60-74 | @ | Bsky | Montana St | 4-4 | 12/9/2008 | ||
| W 87-64 | Ind | CS Bakersfield | 4-9 | 12/13/2008 | |||
| W 88-80 | Bsky | Montana St | 4-4 | 12/22/2008 | |||
| CS Northridge (3-7) | L 85-103 | @ | P10 | Stanford | 9-0 | 11/18/2008 | |
| L 65-67 | @ | Ind | CS Bakersfield | 3-10 | 11/21/2008 | ||
| L 74-85 | @ | MW | New Mexico | 8-5 | 11/24/2008 | ||
| L 72-85 | @ | MAAC | Rider | 6-5 | 11/29/2008 | ||
| L 47-55 | @ | Col | Drexel | 3-6 | 12/1/2008 | ||
| L 67-85 | @ | P10 | UCLA | 9-2 | 12/7/2008 | ||
| W 80-53 | SBC | Denver | 6-6 | 12/9/2008 | |||
| W 99-64 | WCC | Pepperdine | 1-12 | 12/18/2008 | |||
| L 56-72 | @ | MW | San Diego St | 7-3 | 12/22/2008 | ||
| Long Beach (5-7) | L 65-75 | @ | MW | BYU | 10-1 | 11/14/2008 | |
| L 61-68 | @ | B10 | Wisconsin | 8-3 | 11/16/2008 | ||
| W 73-69 OT | Bsky | Weber St | 4-6 | 11/22/2008 | |||
| W 88-82 2 OT | @ | Bsky | Idaho St | 3-9 | 11/25/2008 | ||
| W 82-77 | WAC | New Mexico St | 6-6 | 11/30/2008 | |||
| W 80-61 | WCC | Pepperdine | 1-12 | 12/3/2008 | |||
| L 74-78 2 OT | @ | WCC | San Francisco | 5-7 | 12/6/2008 | ||
| L 63-72 | @ | Bsky | Weber St | 4-6 | 12/11/2008 | ||
| L 55-79 | @ | BigE | Syracuse | 11-1 | 12/13/2008 | ||
| L 61-75 | Bsky | Montana St | 4-5 | 12/20/2008 | |||
| W 76-71 | A10 | Temple | 5-5 | 12/22/2008 | |||
| L 74-86 | @ | P10 | Oregon | 5-6 | 12/29/2008 | ||
| Pacific (6-4) | L 56-68 | @ | P10 | California | 10-2 | 11/15/2008 | |
| W 67-59 | @ | WAC | Nevada | 6-5 | 11/26/2008 | ||
| L 54-72 | @ | P10 | Washington | 8-3 | 11/29/2008 | ||
| W 67-63 OT | Ind | CS Bakersfield | 4-9 | 12/3/2008 | |||
| L 64-66 | WAC | Fresno St | 5-7 | 12/6/2008 | |||
| W 66-60 | WCC | San Francisco | 6-6 | 12/9/2008 | |||
| W 73-55 | @ | WCC | Pepperdine | 1-12 | 12/13/2008 | ||
| W 63-57 | WCC | Santa Clara | 5-6 | 12/20/2008 | |||
| L 65-74 | WCC | St. Mary's | 9-1 | 12/23/2008 | |||
| W 70-51 | @ | Bsky | Sacramento St | 1-11 | 12/30/2008 | ||
| UC Davis (5-8) | L 58-61 | @ | B12 | Iowa State | 8-4 | 11/14/2008 | Cyclone Challenge |
| L 75-81 | vs | Hor | UW Milwaukee | 5-5 | 11/15/2008 | Cyclone Challenge | |
| W 64-55 | vs | WCC | Loyola Marymount | 0-13 | 11/16/2008 | Cyclone Challenge | |
| L 59-68 | @ | SEC | Arkansas | 9-1 | 11/20/2008 | ||
| L 72-75 | WCC | Portland | 7-6 | 11/23/2008 | |||
| W 76-62 | vs | CUSA | Tulane | 5-5 | 11/28/2008 | South Alabama Tournament | |
| L 60-72 | @ | SBC | South Alabama | 7-5 | 11/29/2008 | South Alabama Tournament | |
| L 70-82 | @ | Bsky | Sacramento St | 0-12 | 12/3/2008 | ||
| W 87-86 | Ind | CS Bakersfield | 4-9 | 12/6/2008 | |||
| W 79-61 | @ | SoCon | The Citadel | 3-6 | 12/15/2008 | ||
| L 69-82 | @ | BigS | Presbyterian | 4-8 | 12/17/2008 | ||
| L 89-95 | MAAC | Loyola (Maryland) | 3-9 | 12/21/2008 | |||
| W 72-41 | Ivy | Dartmouth | 1-8 | 12/30/2008 | |||
| UC Irvine (2-9) | L 55-78 | @ | P10 | Southern California | 8-3 | 11/15/2008 | |
| L 69-74 | Bsky | Eastern Washington | 4-6 | 11/19/2008 | |||
| L 77-84 | P10 | Oregon | 5-6 | 11/21/2008 | |||
| L 47-101 | @ | WAC | Idaho | 4-7 | 11/28/2008 | ||
| L 64-78 | @ | Bsky | Eastern Washington | 4-6 | 11/30/2008 | ||
| L 62-74 | @ | WAC | Utah St | 10-1 | 12/2/2008 | ||
| W 71-63 | @ | WCC | Pepperdine | 1-12 | 12/7/2008 | ||
| L 52-65 | vs | SBC | Middle Tenn St | 5-5 | 12/20/2008 | Basketball Travelers Tournament | |
| L 48-57 | @ | MVC | Missouri St | 6-6 | 12/21/2008 | Basketball Travelers Tournament | |
| W 64-51 | vs | MEAC | Norfolk St | 1-9 | 12/22/2008 | Basketball Travelers Tournament | |
| L 52-60 | MW | Utah | 7-4 | 12/27/2008 | |||
| UC Riverside (6-4) | L 52-79 | @ | WAC | New Mexico St | 5-7 | 11/15/2008 | |
| W 61-49 | Bsky | Sacramento St | 1-11 | 11/18/2008 | |||
| W 59-52 | Bsky | Northern Arizona | 1-8 | 11/22/2008 | |||
| W 54-44 | @ | Pat | Colgate | 3-7 | 11/29/2008 | ||
| L 43-59 | @ | B10 | Northwestern | 7-3 | 12/1/2008 | ||
| W 67-63 | Sum | Southern Utah | 3-8 | 12/6/2008 | |||
| W 59-52 | @ | WCC | Loyola Marymount | 0-13 | 12/15/2008 | ||
| W 58-53 | Bsky | Montana | 4-6 | 12/18/2008 | |||
| L 46-56 | @ | WAC | Hawai'i | 7-4 | 12/23/2008 | ||
| L 46-52 | @ | SBC | Denver | 5-7 | 12/28/2008 | ||
| UC Santa Barbara (5-6) | L 59-61 | WAC | Utah St | 10-1 | 11/17/2008 | ||
| L 67-84 | ACC | North Carolina | 11-0 | 11/21/2008 | |||
| L 72-73 | @ | WCC | San Francisco | 5-7 | 11/24/2008 | ||
| W 71-58 | vs | Ind | Winston Salem St | 2-7 | 11/28/2008 | World Vision Invitational | |
| W 57-38 | vs | SLC | Nicholls St | 4-4 | 11/29/2008 | World Vision Invitational | |
| L 59-87 | @ | MVC | Illinois St | 12-0 | 11/30/2008 | World Vision Invitational | |
| W 62-57 | @ | Ind | Utah Valley | 6-4 | 12/4/2008 | ||
| W 81-61 | WCC | Loyola Marymount | 0-13 | 12/13/2008 | |||
| L 63-70 | @ | Bsky | Weber St | 4-7 | 12/17/2008 | ||
| L 51-68 | @ | MW | San Diego St | 7-3 | 12/20/2008 | ||
| W 71-51 | MAC | Ball State | 4-5 | 12/29/2008 |